Kyle Eagen

Dr. Kyle Eagen enriches the academic discourse on cancer biology and chromatin organization as an Assistant Professor at Baylor College of Medicine. With a keen focus on the intricate mechanisms of oncogenic fusion proteins, Dr. Eagen's research delves into the formation of nuclear compartments, particularly through the lens of the BRD4-NUT fusion protein in NUT carcinoma. His work is pivotal in understanding how these proteins drive the organization of chromatin, offering insights into the broader implications for cancer biology. Dr. Eagen's groundbreaking research has identified long-range chromatin interactions that facilitate the formation of a BRD4-NUT-driven nuclear compartment. This discovery underscores the critical role that chromatin organization plays in the progression of cancer, providing a new perspective on how these interactions can be manipulated for therapeutic purposes. By exploring the potential of targeted proteolysis to disrupt these interactions, Dr. Eagen's findings suggest promising avenues for the development of novel treatments for NUT carcinoma. In addition to his research, Dr. Eagen is dedicated to fostering a collaborative and innovative academic environment. His upcoming seminar on February 23rd, from 12:00 pm to 1:30 pm, will offer an in-depth exploration of his latest findings and their implications for cancer therapy. Through his work, Dr. Eagen continues to contribute significantly to the fields of targeted proteolysis and cancer biology, inspiring both his peers and students to push the boundaries of scientific inquiry.